Magnetic Resonance Spectroscopic Imaging with Spiral-based Trajectories - Magnetic Resonance Imaging Group
Conventional Magnetic Resonance Spectroscopic Imaging (MRSI) suffers from both low signal-to-noise (SNR), as well as cumbersome constraints that relate acquisition time to the number of resolved imaging voxels. The development of high-fidelity gradient coils has opened opportunities for fast k-space encoding schemes that are already used in structural imaging. At the same time, receive-coil arrays using up to 128 channels have been developed and reported to produce improved SNR and improved encoding efficiency. In combination with high-field spectroscopic imaging at 7T with excitation RF arrays, these methods will be developed for neuroimaging to study Alzheimer’s disease, brain tumors, stroke, and migraine.